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2-(2-((1-(tert-Butoxycarbonyl)piperidin-4-yl)methyl)-1H-imidazol-1-yl)acetic acid

品牌
Sigma-Aldrich
货号
920533
包装型号
规格纯度
参考价格
3042.47 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

2-(2-((1-(tert-Butoxycarbonyl)piperidin-4-yl)methyl)-1H-imidazol-1-yl)acetic acid is useful as a rigid linker in PROTAC development for targeted protein degradation as well as chemical conjugates. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties. Developed in partnership with ComInnex.

Similar linkers in this series:
920649
920665
920673
920703

其他说明

Portal:Building PROTAC® Degraders for Targeted Protein Degradation

Crosslinkers for Bioconjugation

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式C16H25N3O4
分子量323.39

产品性质

质量水平100
形式powder or crystals
储存温度2-8℃
SMILES stringCC(C)(OC(N1CCC(CC1)CC2=NC=CN2CC(O)=O)=O)C
CC(C)(OC(N1CCC(CC1)CC2=NC=CN2CC(O)=O)=O)C

Sigma-Aldrich

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