产品说明
应用
(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
包装
100 mg in glass bottle
其他说明
Technology Spotlight: Trifuctional Probe Building Blocks
A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS
Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids
Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 5 Based on Select Acetylenic Negative Allosteric Modulators
γ-Secretase Modulator (GSM) Photoaffinity Probes Reveal Distinct Allosteric Binding Sites on Presenilin
基本信息
经验(实验)分子式 | C16H12O3 |
分子量 | 252.26 |
MDL编号 | MFCD28124082 |
产品性质
质量水平 | 100 |
测定 | ≥95% |
形式 | solid |
reaction suitability | reaction type: click chemistry |
储存温度 | −20℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |