产品说明
应用
(11bS)-N,N-dimethyl-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine is a monodentate phosphoramidite (MonoPhos) chiral ligand that can be used:
- In the Cu-catalyzed synthesis of chiral 3-(arylbut-1-yn-1-yl)silane derivatives by reacting N-tosylhydrazones with silyl-substituted alkynes via asymmetric insertion.
- In the Rh-catalyzed asymmetric hydrogenation of R-isopropylcinnamic acid derivative, a key intermediate of renin inhibitor aliskiren.
- In the Rh-catalyzed conjugate addition of arylboronic acids to lactones, enones, and nitroalkenes.
DSM MonoPhos Family of Highly Efficient Privileged Ligands
包装
100 mg in clear glass bottle
500 mg in amber glass bottle
法律信息
经 DSM 授权销售,仅供研究之用。
基本信息
经验(实验)分子式 | C22H26NO2P |
分子量 | 367.42 |
MDL编号 | MFCD04117692 |
PubChem化学物质编号 | 329760980 |
NACRES | NA.22 |
产品性质
旋光性 | [α]22/D 282.0°, c = 1 in chloroform |
mp | 86-94 ℃ |
SMILES string | CN(C)P1Oc2ccc3CCCCc3c2-c4c(O1)ccc5CCCCc45 |
InChI | 1S/C22H26NO2P/c1-23(2)26-24-19-13-11-15-7-3-5-9-17(15)21(19)22-18-10-6-4-8-16(18)12-14-20(22)25-26/h11-14H,3-10H2,1-2H3 |
InChI key | OIZQADYWBXZQKE-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |