BAPTA/AM-CAS 126150-97-8-Calbiochem

产品说明

一般描述

Membrane-permeable form of BAPTA. Can be loaded into a wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA. Prevents cocaine-induced ventricular fibrillations. Induces inactivation of protein kinase C. Also inhibits thapsigargin-induced apoptosis in rat thymocytes.
Membrane-permeable form of BAPTA. Can be loaded into a wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA.Prevents cocaine-induced ventricular fibrillations. Abolishes vitamin D₃-induced increase in intracellular Ca²⁺. Induces inactivation of protein kinase C. Also inhibits thapsigargin-induced apoptosis in rat thymocytes.

包装

25, 100 mg in Plastic ampoule
Packaged under inert gas

警告

Toxicity: Irritant (B)

重悬

Following reconstitution, aliquot, purge with inert gas and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

其他说明

Bissonnette, M., et al. 1994. Am. J. Physiol.267, G465.
Jiang, S., et al. 1994. Exp. Cell Res.212, 84.
Billman, G.E. 1993. Am. J. Physiol. 265, H1529.
Dieter, P., et al. 1993. Biol. Chem. Hoppe Seyler 374, 171.
Harrison, S.M., and Bers, D.M. 1987. Biochim. Biophys. Acta 925, 133.
Harrison, S.M., and Bers, D.M. 1987. J. Biophys.51, 102A.
Marban, E., et al. 1986. J. Clin. Invest.78, 1185.
Tsien, R.Y. 1981. Nature290, 527.
Tsien, R.Y. 1980. Biochemistry19, 2396.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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