产品介绍:
产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
VU0405601 is a hERG (the human Ether-à-go-go-Related Gene) agonist that increased the IC50 of dofetilide from 38.7 nM to 76.3 nM. VU0405601 protects against arrhythmias induced by hERG inhibition.
基本信息
经验(实验)分子式 | C17H13BrN2O2 |
分子量 | 357.20 |
MDL编号 | MFCD05995040 |
PubChem化学物质编号 | 329825580 |
NACRES | NA.77 |
产品性质
测定 | ≥98% (HPLC) |
形式 | powder |
储存条件 | desiccated |
颜色 | white to beige |
溶解性 | DMSO: 20 mg/mL, clear |
储存温度 | 2-8℃ |
SMILES string | BrC1=C2C=CC=CC2=CC=C1OCC(NC3=CC=CN=C3)=O |
InChI | 1S/C17H13BrN2O2/c18-17-14-6-2-1-4-12(14)7-8-15(17)22-11-16(21)20-13-5-3-9-19-10-13/h1-10H,11H2,(H,20,21) |
InChI key | WLLRAGBPCSOJNH-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H315 - H319 - H335 |
预防措施声明 | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |