产品介绍：
产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
VU0361737 is an mGluR4-specific positive allosteric modulator (PAM) with greater than 50 fold selectivity over other mGluR subtypes. The EC50 values for human and rat mGlu4 are 240 and 110 nM, respectively, compared to greater than 10 mM for all other mGluRs.
特点和优势
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
| 经验(实验)分子式 | C13H11ClN2O2 |
| 分子量 | 262.69 |
| MDL编号 | MFCD16618402 |
| PubChem化学物质编号 | 329825444 |
| NACRES | NA.77 |
产品性质
| 测定 | ≥98% (HPLC) |
| 形式 | film |
| 颜色 | white |
| 溶解性 | DMSO: 15 mg/mL (clear solution) |
| 储存温度 | 2-8℃ |
| SMILES string | COc1cc(NC(=O)c2ccccn2)ccc1Cl |
| InChI | 1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17) |
| InChI key | ARYUXFNGXHNNDM-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 - H319 |
| 预防措施声明 | P305 + P351 + P338 |
| 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
