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VTCN1 human

品牌
Sigma-Aldrich
货号
SRP6418
规格纯度
recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)
参考价格
3563.77 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.

外形

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

重悬

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in HEK 293 cells
标签6-His tagged (C-terminus)
测定≥90% (SDS-PAGE)
形式lyophilized
分子量calculated mol wt 26.1 kDa
observed mol wt 45-60 kDa (DTT-reduced. Protein migrates due to glycosylation. Phe 29 is the predicted N-terminal.)
包装pkg of 10 μg
pkg of 50 μg
UniProt登记号Q7Z7D3
运输wet ice
储存温度−20℃
Gene Informationhuman ... VTCN1(79679)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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