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Ticagrelor

替格瑞洛

品牌
Sigma-Aldrich
CAS
274693-27-5
货号
SML2482
规格纯度
≥98% (HPLC)
参考价格
742.66 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Ticagrelor (AZD6140) is a cyclopentyl-triazolopyrimidine.

生化/生理作用

Ticagrelor is an antithrombotic antiplatelet drug that acts by direct and reversible competitive inhibition of the adensoine purinoceptor P2Y12 receptor. It has clinical benefits in people affected with acute coronary syndrome. It might also play a beneficial role on endothelial function. Ticagrelor can prevent the uptake of adenosine by human erythrocytes and can promote the liberation of adenosine triphosphate (ATP) from human erythrocytes.

基本信息

经验(实验)分子式C23H28F2N6O4S
分子量522.57
MDL编号MFCD09954148

产品性质

测定≥98% (HPLC)
形式powder
旋光性[α]/D -55 to -65°, c = 0.2 in methanol
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度−20℃
SMILES stringCCCSC1=NC(N[C@@]2([H])[C@@](C3=CC=C(F)C(F)=C3)([H])C2)=C4C(N([C@@]5([H])[C@H](O)[C@H](O)[C@@H](OCCO)C5)N=N4)=N1
InChI1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15+,16+,17-,19-,20+/m0/s1
InChI keyOEKWJQXRCDYSHL-FNOIDJSQSA-N
Gene Informationhuman ... P2RY12(64805)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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