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SFRP1/SARP2 human

品牌
Sigma-Aldrich
货号
SRP6463
规格纯度
recombinant, expressed in HEK 293 cells, ≥92% (SDS-PAGE)
参考价格
3780.71 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Secreted frizzled-related protein 1 (SFRP1) also known as Secreted apoptosis-related protein 2 (SARP2), FRP, FRP1, is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The Secreted frizzled-related protein (SFRP) family consists of five secreted glycoproteins in humans (SFRP1, SFRP2, SFRP3, SFRP4, SFRP5) that act as extracellular signaling ligands. SFRP1 / SARP-2 is widely expressed and absent from lung, liver and peripheral blood leukocytes, and with the highest levels in heart and fetal kidney. SARP2 / SFRP-1 is a 35 kDa prototypical member of the SFRP family. SARP2 / FRP-1 acts as a biphasic modulator of Wnt signaling, counteracting Wnt-induced effects at high concentrations and promoting them at lower concentrations.

外形

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.

重悬

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in HEK 293 cells
标签6-His tagged (C-terminus)
测定≥92% (SDS-PAGE)
形式lyophilized
分子量calculated mol wt 33.4 kDa
observed mol wt 38 kDa (DTT-reduced. Protein migrates due to glycosylation. Ser 32 is the predicted N-terminal.)
包装pkg of 10 μg
杂质<1 EU/μg endotoxin (LAL test)
UniProt登记号Q8N474
运输wet ice
储存温度−20℃
Gene Informationhuman ... SFRP1(6422)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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