产品说明
应用
Salsalate was used to study the effect on palmitate-induced insulin resistance and hepatic steatosis in obese rats.
包装
50, 250 mg in glass bottle
生化/生理作用
Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.
基本信息
经验(实验)分子式 | C14H10O5 |
分子量 | 258.23 |
EC 号 | 209-027-4 |
MDL编号 | MFCD00020252 |
PubChem化学物质编号 | 329825134 |
NACRES | NA.77 |
产品性质
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to tan |
溶解性 | DMSO: ≥15 mg/mL |
储存温度 | room temp |
SMILES string | OC(=O)c1ccccc1OC(=O)c2ccccc2O |
InChI | 1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17) |
InChI key | WVYADZUPLLSGPU-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H400 |
预防措施声明 | P273 - P301 + P312 + P330 |
危险分类 | Acute Tox. 4 Oral - Aquatic Acute 1 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |