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Salsalate

品牌
Sigma-Aldrich
CAS
552-94-3
货号
SML0070
规格纯度
≥98% (HPLC)
参考价格
1509.3 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Salsalate was used to study the effect on palmitate-induced insulin resistance and hepatic steatosis in obese rats.

包装

50, 250 mg in glass bottle

生化/生理作用

Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.

基本信息

经验(实验)分子式C14H10O5
分子量258.23
EC 号209-027-4
MDL编号MFCD00020252
PubChem化学物质编号329825134
NACRESNA.77

产品性质

测定≥98% (HPLC)
形式powder
颜色 white to tan
溶解性DMSO: ≥15 mg/mL
储存温度room temp
SMILES stringOC(=O)c1ccccc1OC(=O)c2ccccc2O
InChI1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17)
InChI keyWVYADZUPLLSGPU-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H302 - H400
预防措施声明P273 - P301 + P312 + P330
危险分类Acute Tox. 4 Oral - Aquatic Acute 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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