产品介绍:
产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
RQ-00203078 is an orally available potent and selective TRPM8 antagonist that potently reduces cation currents induced by menthol and other TRPM8 agonists. RQ-00203078 inhibits HSC3 and HSC4 oral squamous carcinoma cell migration and invasion in vitro.
基本信息
经验(实验)分子式 | C21H13ClF6N2O5S |
分子量 | 554.85 |
MDL编号 | MFCD29049510 |
PubChem化学物质编号 | 329825488 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
溶解性 | DMSO: 25 mg/mL, clear |
储存温度 | 2-8℃ |
SMILES string | ClC1=CC(C(F)(F)F)=CN=C1N(S(C2=CC=C(C(O)=O)C=C2)(=O)=O)CC3=CC=C(OC(F)(F)F)C=C3 |
InChI | 1S/C21H13ClF6N2O5S/c22-17-9-14(20(23,24)25)10-29-18(17)30(11-12-1-5-15(6-2-12)35-21(26,27)28)36(33,34)16-7-3-13(4-8-16)19(31)32/h1-10H,11H2,(H,31,32) |
InChI key | IJGQFZYYEHCCIZ-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H315 - H319 - H335 |
预防措施声明 | P305 + P351 + P338 |
危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |