产品说明
一般描述
RIPK5 is a dual specificity serine/threonine and tyrosine protein kinase that is a member of the RIPK family. RIPK5 is widely expressed in vertebrates with broad distributed in the central nervous system, and deregulated in certain human cancers. RIPK5 has been shown to function as a regulator of cell death. Overexpression of RIPK5 leads to cell death as evidenced by DNA fragmentation. RIPK5 induces both caspase-dependent and caspase-independent cell death, and N- and C-terminal RIPK5 deletion mutants retained the ability to induce cell death.
外形
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
制备说明
after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles
法律信息
PRECISIO is a registered trademark of sigma-aldrich Co. LLC
基本信息
| NACRES | NA.32 |
产品性质
| 重组 | expressed in baculovirus infected Sf9 cells |
| 产品线 | PRECISIO® Kinase |
| 测定 | ≥70% (SDS-PAGE) |
| 形式 | buffered aqueous glycerol solution |
| specific activity | 5-7 nmol/min·mg |
| 分子量 | ~140 kDa |
| NCBI登记号 | NM_015375 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... DSTYK(25778) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
