产品说明
一般描述
PTPRF or LAR is a member of the protein tyrosine phosphatase family with an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains. PTPRF has been shown to function in the regulation of epithelial cell-cell contacts at adherents junctions as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance.
外形
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
制备说明
after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles
基本信息
NACRES | NA.32 |
产品性质
重组 | expressed in E. coli |
测定 | ≥70% (SDS-PAGE) |
形式 | buffered aqueous glycerol solution |
specific activity | 386-522 nmol/min·mg |
分子量 | ~93 kDa |
NCBI登记号 | NM_002840 |
运输 | dry ice |
储存温度 | −70℃ |
Gene Information | human ... PTPRF(5792) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |