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Phthalimidooxy-dPEG®4-NHS ester

品牌
Sigma-Aldrich
货号
QBD10011
包装型号
规格纯度
参考价格
1148.19 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

特点和优势

Phthalimidooxy-dPEG®4-NHS ester allows introduction of an oxyamine function onto a target molecule for cross-linking proteins or for creating stable conjugates with the target molecule. The oxyamine function is protected by a phthalimido protecting group on one end of the spacer arm, and the spacer is installed on the target molecule with the amine-reactive N-hydroxysuccinimide (NHS) group on the other end of the spacer. The single molecular weight dPEG® spacers have precise length for spatial control. They are hydrophilic and non-immunogenic. The dPEG® spacers improve water solubility and reduce aggregation and precipitation of proteins. The phthalimido protecting group can be removed using hydrazine. The oxyamine group exposed after deprotection can be reacted with an aldehyde- or ketone-containing molecule to form an oxime bond linking the two molecules. These reagents can be used with any protein, peptide, or small molecule that has a free amine.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

基本信息

经验(实验)分子式C23H28N2O11
分子量508.48
MDL编号MFCD28155511
PubChem化学物质编号329823874
NACRESNA.22

产品性质

测定>90%
形式solid or viscous liquid
reaction suitabilityreagent type: cross-linking reagent
reactivity: amine reactive
reagent type: cross-linking reagent
reactivity: thiol reactive
聚合物结构设计shape: linear
functionality: heterobifunctional
运输ambient
储存温度−20℃
SMILES stringO=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCON2C(C(C=CC=C3)=C3C2=O)=O

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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