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PC4, serine mutations human

品牌
Sigma-Aldrich
货号
SRP2024
规格纯度
recombinant, expressed in E. coli, ≥80% (SDS-PAGE)
参考价格
5702.53 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

Human PC4 is a non-TAF transcription coactivator that mediates activator-dependent transcription by RNA polymerase II in vitro through most tested activators. The function of PC4 is through interactions with transcriptional activators and the basal transcription machinery. It is negatively regulated by casein kinase II phosphorylation both in vitro and in vivo. PC4 strongly binds single stranded DNA and the region essential for the single stranded DNA binding activity was mapped around residue 77. A single amino acid change at position 77 (F to P) abolishes both ds- and ss-DNA binding activity.

外形

Clear and colorless frozen liquid solution

制备说明

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

基本信息

NACRESNA.26

产品性质

生物来源human
重组expressed in E. coli
测定≥80% (SDS-PAGE)
形式frozen liquid
分子量 ~14.4 kDa
包装pkg of 10 μg
浓度1000 μg/mL
颜色clear colorless
NCBI登记号NM_006713
UniProt登记号P53999
运输dry ice
储存温度−70℃
Gene Informationhuman ... SUB1(10923)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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