产品说明
包装
10, 50 mg in glass bottle
生化/生理作用
PA-824 is an anti-tuberculosis drug.
PA-824 is a pro-drug that has an effect on both replicating and non-replicating Mycobacterium tuberculosis. It is activated by deazaflavin (cofactor F420)-dependent nitroreducase.
PA-824 is an anti-tuberculosis drug that exhibits multiple mechanism of action, including both cell wall inhibition and respiratory poisoning.
基本信息
经验(实验)分子式 | C14H12F3N3O5 |
分子量 | 359.26 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
旋光性 | [α]/D -40 to -48°, c = 1 in methanol |
颜色 | white to brown |
溶解性 | DMSO: 5 mg/mL, clear (warmed) |
储存温度 | −20℃ |
InChI | 1S/C14H12F3N3O5/c15-14(16,17)25-10-3-1-9(2-4-10)7-23-11-5-19-6-12(20(21)22)18-13(19)24-8-11/h1-4,6,11H,5,7-8H2/t11-/m0/s1 |
InChI key | ZLHZLMOSPGACSZ-NSHDSACASA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H315 - H319 - H335 |
预防措施声明 | P280 - P304 + P340 + P312 - P305 + P351 + P338 - P337 + P313 |
危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |