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Nepafenac

品牌
Sigma-Aldrich
CAS
78281-72-8
货号
SML0288
规格纯度
≥98% (HPLC)
参考价格
730.94 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery.
Nepafenac, a prodrug of amfenac, is used in the treatment of diabetic retinopathy. It is metabolized to its active form through intraocular enzymatic hydrolysis. Nepafenac has a molecular weight of 254.28 kDa and effectively penetrates through the cornea. Its molecule structure enables nepafenac to possess better permeability. Nepafenac has a low inhibitory effect on cyclooxygenase.

基本信息

经验(实验)分子式C15H14N2O2
分子量254.28
MDL编号MFCD08067732
PubChem化学物质编号329825296
NACRESNA.77

产品性质

测定≥98% (HPLC)
形式powder
颜色faintly yellow to dark yellow
溶解性DMSO: ≥5 mg/mL
储存温度room temp
SMILES stringNC(=O)Cc1cccc(c1N)C(=O)c2ccccc2
InChI1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)
InChI keyQEFAQIPZVLVERP-UHFFFAOYSA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS09
警示用语:Warning
危险声明H400
预防措施声明P273
危险分类Aquatic Acute 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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