产品说明
一般描述
Myelin basic protein (MBP) is the second most ample protein in the central nervous system (CNS) insulating brain nerve cells and the spinal cord. This protein belongs to the family of intrinsically unstructured proteins. MBP binds to the cytosolic surface of the oligodendrocyte membrane. The MBP gene is located on the human chromosome at 18q23.
免疫原
Purified recombinant fragment of human MBP expressed in E.coli.
Mouse monoclonal antibody raised against MBP
应用
Monoclonal Anti-MBP antibody produced in mouse has been used in:
- immunofluorescence (1:400)
- western blotting (1:1000)
- immunostaining (1:250)
生化/生理作用
Myelin basic protein (MBP) is considered as an ‘executive molecule of myelin′ as it participates in the formation of central nervous system (CNS) myelin. Increased levels of MBP in the cerebrospinal fluid (CSF) are observed in acute neurological disorders like traumatic brain injury, cerebrovascular accidents, and exacerbating multiple sclerosis. It is also observed at higher levels during chronic progressive disorders like tumor cerebri, dementia, and metabolic disorders.
外形
Ascitic fluid containing 0.03% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | ascites fluid |
| antibody product type | primary antibodies |
| 克隆 | 2H9, monoclonal |
| 分子量 | 33 kDa |
| species reactivity | human |
| technique(s) | direct ELISA: 1:10,000 flow cytometry: 1:200-1:400 immunohistochemistry: 1:200-1:1,000 indirect immunofluorescence: 1:200-1:1,000 western blot: 1:500-1:2,000 |
| 同位素/亚型 | IgG1 |
| NCBI登记号 | NM_001025100 |
| UniProt登记号 | P02686 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... MBP(4155) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
