产品说明
一般描述
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)
免疫原
MAP4K4 (NP_663719, 611 a.a. ~ 710 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VHPALQRPAEPQVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDPCPPSRSEVLSQSSDSKSEAPDPTQKAWSRSDSDEVPPRVPVRTTSRSPV
外形
Solution in phosphate buffered saline, pH 7.4
基本信息
NACRES | NA.41 |
产品性质
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 2D4, monoclonal |
形式 | buffered aqueous solution |
分子量 | antigen ~37 kDa |
species reactivity | human |
technique(s) | capture ELISA: suitable indirect ELISA: suitable western blot: 1-5 μg/mL |
同位素/亚型 | IgG2aκ |
NCBI登记号 | NM_145686 |
UniProt登记号 | O95819 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... MAP4K4(9448) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |