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Monoclonal Anti-LIG3 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB2702141
包装型号
规格纯度
clone 1F3
参考价格
5732.41 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97kDa (§-form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.

免疫原

Recombinant full-length human DNA Ligase III-b.

应用

Suggested starting dilutions are as follows: Blocking: Assay-dependent dilution, ICC/IF: Assay-dependent dilution, IP: Assay-dependent dilution, WB: Assay-dependent dilution, PLA: Assay-dependent dilution. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生化/生理作用

There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97kDa (§-form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Phosphate-buffered saline, no preservative added.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆1F3, monoclonal
形式liquid
分子量 100 kDa
species reactivitymouse, chicken, human
浓度1 mg/mL
technique(s)immunocytochemistry: suitable
immunofluorescence: suitable
immunoprecipitation (IP): suitable
proximity ligation assay: suitable
western blot: suitable
同位素/亚型IgG1
UniProt登记号P49916
运输wet ice
储存温度−20℃
Gene Informationhuman ... LIG3(3980)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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