产品说明
一般描述
Interleukin 33 (IL-33) is a potent immunomodulatory cytokine that belongs to the IL-1 family. It is highly expressed in endothelial venules, endothelial cells and epithelium. The gene encoding this protein is localized on human chromosome 9p24.1.
免疫原
Mouse monoclonal IL-33 antibody was raised against the recombinant IL-33 protein.
生化/生理作用
Interleukin 33 (IL-33) functions as an extracellular cytokine and also translocates to the nucleus where it inhibits gene expression. IL-33 enhances the secretion of inflammatory cytokines and is associated with T-helper 2-type immune responses. It has been linked to chronic inflammatory diseases. High levels of IL-33 have been observed in the serum of patients with hepatocellular carcinoma and gastric cancer. Polymorphisms in this gene as well as its receptor are linked with atopic dermatitis, allergies and asthma.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied in PBS with 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 12H6D12, monoclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human, mouse |
| technique(s) | immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
| NCBI登记号 | NP_254274 |
| UniProt登记号 | O95760 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... IL33(90865) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
