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Monoclonal Anti-Glun2A/Nr2A-Apc antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB5200898
规格纯度
clone S327-95, purified immunoglobulin
参考价格
7828.17 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The GRIN2A (glutamate ionotropic receptor NMDA (N-methyl-D-aspartate) type subunit 2A) gene is mapped to human chromosome 16p13.2. It codes for a transmembrane ligand-gated ion channel called N-methyl-D-aspartate glutamate receptor α2 subunit.

免疫原

Fusion protein amino acids 75-325 (extracellular N-terminus) of rat GluN2A/NR2A

生化/生理作用

The GRIN2A (glutamate ionotropic receptor NMDA (N-methyl-D-aspartate) type subunit 2A) gene is associated with focal epilepsy and impaired speech. NMDA glutamate receptor α2 subunit is involved in neuron development, maintains synaptic plasticity and is associated with memory. GRIN2A is related to schizophrenia and Alzheimer′s disease. Mutations in GRIN2A gene upregulates NMDA action and might lead to melanoma tumors. NMDA participates in apoptosis and proliferation of cancer cells.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

PBS pH7.4, 50% glycerol, 0.09% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物Allophycocyanin conjugate
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆S327-95, monoclonal
形式buffered aqueous solution
分子量antigen predicted mol wt 170 kDa
species reactivityrat, mouse, human
浓度1 mg/mL
technique(s)immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型IgG2a
NCBI登记号NP_036705.3
UniProt登记号Q12879
运输wet ice
储存温度−20℃
Gene Informationrat ... Grin2a(24409)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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