产品说明
一般描述
Monoclonal Anti-EXOC2 (mouse IgG1 isotype) is derived from the hybridoma 5S8A10 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. Exocyst complex component 2 (EXOC2) gene is located in the human chromosome at 6p25.3. EXOC2 protein is a component of the large multiprotein complex.
特异性
Monoclonal Anti-EXOC2 recognizes human, monkey, chicken, dog, hamster, rat and mouse EXOC2.
免疫原
recombinant protein corresponding to full-length rat brain EXOC2 subunit
应用
Monoclonal Anti-EXOC2 antibody produced in mouse may be used in:
- immunoblotting
- immunocytochemistry
- flow cytometry
- immunofluorescence
生化/生理作用
Exocyst complex component 2 (EXOC2) is involved in vesicle trafficking and maintenance. It is also involved in the intercellular transfer of viral proteins and virions. EXOC2 is responsible for host defense and regulation of cell death. It interacts with Ral proteins, which is involved in cell polarity, cell motility and cytokinesis. Mutations in the EXOC2 gene is associated with dysmorphism, brain abnormalities and developmental delay. It is also associated with epilepsy and poor motor skills.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
储存及稳定性
For extended storage, freeze at -20 ℃ in working aliquots. Repeated freezing and thawing,or storage in “frost-free” freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 5S8A10, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~95 kDa |
| species reactivity | rat, mouse, chicken, human, monkey, canine, hamster |
| 浓度 | ~1.0 mg/mL |
| technique(s) | flow cytometry: 10 μg/test using HeLa cells immunoblotting: 1-2 μg/mL using HeLa total cell extracts immunocytochemistry: suitable immunofluorescence: 2.5-5 μg/mL using HeLa cells |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | Q96KP1 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | rat ... Exoc2(171455) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
