产品说明
免疫原
Amino acids 1-153 of human ER-beta expressed in E. coli.
应用
Suggested starting dilutions are as follows: Dot: Assay-dependent dilution, FACS: Assay-dependent dilution, ICC/IF: Assay-dependent dilution, IHC: Assay-dependent dilution, IHC-P: Assay-dependent dilution, WB: 1:1000-1:10000, ChIP assay: Assay-dependent dilution. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
生化/生理作用
The human ER-beta is a newly discovered estrogen receptor initially cloned and characterized from testis. The size and structure of ER-beta is very similar to ER-alpha with the ligand and DNA binding domains being highly conserved, while the amino terminus which serves as their transactivation domain has diverged significantly. Similar in function to ER-alpha ER-beta binds to estrogen with a high affinity and regulates estrogen specific gene activation through direct interaction with estrogen response elements (ERE′s).
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Phosphate-buffered saline, no preservative added.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 14C8 monoclonal |
| 形式 | liquid |
| 分子量 | 58-60 kDa |
| species reactivity | human, mouse, monkey |
| 浓度 | 1 mg/mL |
| technique(s) | ChIP: suitable dot blot: suitable flow cytometry: suitable immunocytochemistry: suitable immunofluorescence: suitable immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable western blot: 1:1000-1:10000 |
| 同位素/亚型 | IgG2b |
| UniProt登记号 | Q92731 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ESR2(2100) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
