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Monoclonal Anti-CEP164 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB2702133
包装型号
规格纯度
参考价格
6262.8 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The centrosomal protein 164 (CEP164) is expressed at the distal ends of the mother centriole. This protein consists of an N-terminal WW domain and three coiled-coil regions. The CEP164 gene is located on the human chromosome at 11q23.3.

免疫原

Human Cep164

应用

Monoclonal Anti-CEP164 antibody produced in mouse has been used in immunoblotting (5 μg/ml).

生化/生理作用

The centrosomal protein 164 (CEP164) plays an important role in the synthesis of the primary cilium. This protein interacts with several proteins during ciliogenesis such as Rabin-8, Tau tubulin kinase‐2 (TTBK2), coiled-coil domain containing 41 (CCDC41), and dishevelled (DVL). CEP164 protein is also involved in G2/M checkpoint and nuclear divisions. This protein is a key player in the DNA damage-activated ataxia telangiectasia mutated (ATM)/Rad3-related (ATR) signaling cascade since it is required for the proper phosphorylation of the histone family member X (H2AX), replication protein A (RPA), checkpoint kinase 1 and 2 (CHK1/2). Mutations in the CEP164 gene leads to a condition known as nephronophthisis (NPHP)‐ elated ciliopathies.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Phosphate-buffered saline, no preservative added.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆13
monoclonal
形式liquid
species reactivityhuman
浓度1 mg/mL
technique(s)immunocytochemistry: suitable
immunofluorescence: suitable
immunoprecipitation (IP): suitable
western blot: 1:500-1:3000
同位素/亚型IgG1
UniProt登记号Q9UPV0
运输wet ice
储存温度−20℃
Gene Informationhuman ... CEP164(22897)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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