位置:首页 > 品牌 > Sigma-Aldrich >

Monoclonal Anti-CDH13 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB4200672
规格纯度
clone CAD-5, purified from hybridoma cell culture
参考价格
6732.28 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Monoclonal Anti-CDH13 (mouse IgG1 isotype) is derived from the hybridoma CAD-5 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. Cadherin 13 (CDH13) is a member of the cadherins multigene family of single-chain glycoprotein receptors. It is a glycosylphosphatidylinositol (GPI)- anchored member and a low-density lipoprotein (LDL)-binding protein usually found in smooth muscle. CDH13 is present in the brain and cardiovascular system. It is mapped on the human chromosome at 16q23.3.

特异性

Monoclonal Anti-CDH13 recognizes human Cadherin 13.

免疫原

N-terminal His-tagged recombinant protein of human Cadherin 13

应用

Monoclonal Anti-CDH13 antibody produced in mouse may be used in:

  • immunoblotting
  • immunoprecipitation
  • immunohistochemistry

生化/生理作用

Cadherin (CDH) is involved in mediating Ca2+-dependent cell-cell adhesion. Abnormalities in the CDH13 gene have been identified in human malignancies. Promoter methylation of CDH13 results in gene silencing in non-small cell lung carcinoma (NSCLC). CDH13 is involved in cell migration, axon guidance and neurite growth. It is also associated with attention-deficit/hyperactivity disorder (ADHD). CDH13 is also involved in autism spectrum disorders, bipolar disorder, schizophrenia and depression.

外形

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide

储存及稳定性

For continuous use, store at 2–8 ℃ for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

法律信息

ExtrAvidin is a registered trademark of sigma-aldrich Co. LLC

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆CAD-5, monoclonal
形式buffered aqueous solution
species reactivityhuman
浓度~1 mg/mL
technique(s)immunoblotting: 5-10 μg/mL using whole extract of human HeLa cells.
immunohistochemistry: 5-10 μg/mL using Biotin/ExtrAvidin®-Peroxidase staining system of heat-retrieved formalin-fixed, paraffin-embedded human heart sections
immunoprecipitation (IP): 5-10 μg/mL using whole extract of human HeLa cells.
同位素/亚型IgG1
UniProt登记号P55290
运输dry ice
储存温度−20℃
Gene Informationhuman ... CDH13(1012)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号