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Monoclonal Anti-CD11c-APC antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB4700391
规格纯度
clone BU15, purified immunoglobulin, buffered aqueous solution
参考价格
5670.5 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Cluster of differentiation 11c (CD11c), also known as integrin subunit α X (ITGAX), is an antigen receptor, encoded by the gene mapped to human chromosome 16p11.2. The encode protein belongs to the adhesion molecule integrin family and is mainly expressed in natural killer cells, macrophages and even some activated B and T cells.
The antibody BU15 reacts with CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.

免疫原

Dendritic cells of synovial fluid

应用

The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (1 mL) is sufficient for 100 tests.

生化/生理作用

Cluster of differentiation 11c (CD11c) delivers co-stimulatory signals to activated lymphocytes. Elevated expression of the gene decreased the risk of death and relapse in gastric cancer (GC) patients. The protein can be considered as an alternative prognosis marker for GC. Overexpression of CD11c in CD8+ cells might lead to the development of Behcet′s disease (BD).

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物Allophycocyanin conjugate
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆BU15, monoclonal
形式buffered aqueous solution
species reactivitycanine, monkey, human
technique(s)flow cytometry: suitable
同位素/亚型IgG1
NCBI登记号NM_000887.3
UniProt登记号P20702
运输wet ice
储存温度2-8℃
Gene Informationhuman ... ITGAX(3687)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

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