产品说明
一般描述
CD14 (cluster of differentiation 14) is a myelomonocytic differentiation antigen, encoded by the gene mapped to human chromosome 5q23-31. It is mainly expressed by monocytes, macrophages and activated granulocytes.
免疫原
A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria
应用
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.
生化/生理作用
CD14 (cluster of differentiation 14) serves as an important receptor of bacterial lipopolysaccharide (LPS). CD14 and LPs complex interacts with toll-like receptor 4 and enhances the expression of inflammatory mediators, including tumor necrosis factor (TNF)- and interleukin (IL)-1, via p38 mitogen-activated protein kinase and nuclear factor-B pathway. Mutation in the gene is associated with the development of myeloid leukemias and generalized chronic periodontitis (GCP).
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.44 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | phycoerythrin (R-PE) conjugate |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | MEM-15, monoclonal |
| 形式 | buffered aqueous solution |
| species reactivity | nonhuman primates, human |
| technique(s) | flow cytometry: suitable |
| 同位素/亚型 | IgG1 |
| NCBI登记号 | NM_000591.3 |
| UniProt登记号 | P08571 |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| Gene Information | human ... CD14(929) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
