产品说明
一般描述
CD63 belongs to the transmembrane 4 superfamily (TM4SF). CD63 is an integral membrane glycoprotein expressed in late endosomes and lysosomes, and is also present in the platelet dense granule membrane.
免疫原
HPB-ALL T cell line
应用
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.
生化/生理作用
CD63 is one of the platelet activation marker, which plays a vital role in platelet aggregation, adhesion to collagen, uptake of oxidized low-density lipoprotein (LDL) in vitro and regulation of angiogenesis. Improved metabolic control deduce platelet activation marker in the type-2 diabetes patients and helps in reducing development of diabetic late complications. Inadequate expression of CD63 results in the autosomal recessive inherited disorder, Hermansky-Pudlak syndrome. CD63 is associated with various cellular functions such as cellular adhesion, cell differentiation, migration, carcinogenesis, and tumor progression. CD63 is highly expressed in initial stage of Merkel cell carcinoma and decreased in later stages; therefore, CD63 is considered to be a potential prognostic factor for this malignancy.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | FITC conjugate |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | MEM-259, monoclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | flow cytometry: suitable |
| 同位素/亚型 | IgG1 |
| NCBI登记号 | NM_001040034.1 |
| UniProt登记号 | P08962 |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| Gene Information | human ... CD63(967) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
