产品说明
一般描述
C-C motif chemokine ligand 19 (CCL19) is a homeostatic chemokine expressed in secondary lymphoid tissue. The gene encoding it is localized on human chromosome 9p13.
免疫原
CCL19 (AAH27968, 1 a.a. ~ 98 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MALLLALSLLVLWTSPAPTLSGTNDAEDCCLSVTQKPIPGYIVRNFHYLLIKDGCRVPAVVFTTLRGRQLCAPPDQPWVERIIQRLQRTSAKMKRRSS
生化/生理作用
C-C motif chemokine ligand 19 (CCL19) is involved in adaptive immune system. It recruits monocytes, macrophages, antigen presenting dendritic cells and naive T-cells to secondary lymphoid organs by activation of C-C motif chemokine receptor 7 (CCR7). The protein controls cell migration and angiogenesis in many types of diseases. CCL19 is upregulated in human atherosclerotic lesions. It is also involved in the development of various inflammatory disorders such as asthma, atherosclerosis and rheumatoid arthritis, and might be associated with the pathogenesis of rickettsiae infection.
外形
Clear solution
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | ascites fluid |
| antibody product type | primary antibodies |
| 克隆 | 3E9, monoclonal |
| 分子量 | antigen ~36.89 kDa |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable |
| 同位素/亚型 | IgMκ |
| NCBI登记号 | BC027968 |
| UniProt登记号 | Q99731 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CCL19(6363) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
