产品说明
一般描述
2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a derivative of the synthetic isothiazolinone.
应用
- Methylisothiazolinone (MIT) has been used as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and role in apoptotic cell death.
- MIT is used to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites.
- MIT is an efficient antifungal and antibacterial, and a substitute to thimerosal.
生化/生理作用
2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a skin sensitizer known to cause contact dermatitis and allergy. It is extensively used in the cosmetic industry as a preservative. MIT is a neurotoxin and its prolonged exposure may lead to neuronal death and inhibition of neurite outgrowth. It is also a potent antibacterial agent.
产品性质
质量水平 | 200 |
浓度 | 1% 10 mg/mL in water |
作用机制 | protein synthesis | interferes |
抗生素抗菌谱 | fungi |
储存温度 | 2-8℃ |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H290 - H315 - H317 - H319 - H412 |
预防措施声明 | P234 - P261 - P273 - P280 - P302 + P352 - P305 + P351 + P338 |
危险分类 | Aquatic Chronic 3 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 |
储存分类代码 | 8B - Non-combustible, corrosive hazardous materials |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |