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Microbial Transglutaminase

品牌
Sigma-Aldrich
货号
SAE0159
规格纯度
lyophilized powder, ≥12 units/mg protein
参考价格
3973.11 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Transglutaminases (TG) are a family of enzymes that catalyze isopeptide bond formation. This bond formation occurs between the γ-carboxyamide group of glutamine and various primary amines (primarily the ε-amino group of lysine). The resulting intermolecular or intramolecular cross-linking of transglutaminase is highly stable and shows high resistance to proteolytic degradation. The transglutaminase crosslinking activity support the formation of blood clots , skin and hair. On the other hand, TG is now being implicated in Celiac disease as well as in Huntington and Parkinson diseases. Historically, Microbial transglutaminase has been heavily used in the food industry. Microbial TG is often preferred for newer applications (such as site-specific protein modification and antibody drug conjugation) due to its small molecular weight and lack of calcium dependency when compared to the mammalian forms.

应用

Microbial Transglutaminase has been used for:

  • Protein cross-linking & site-specific labeling
  • Antibody Drug Conjugation
  • 3D bioprinting bioink preparation
  • Food related immunogenicity/pathogenicity related research

特点和优势

  • Small (~38kDa) and calcium independent enzyme
  • Highly purified lyophilized enzyme
  • Consistent and reproducible activity
  • Characterized for endotoxin content

制备说明

For R&D use only. Not for drug, household, or other uses. Please consult the Safety Data Sheet for information regarding hazards and safe handling practices

储存及稳定性

Store the freeze-dried product at –20 ℃. It is recommended to store the reconstituted protein in working aliquots at –20 ℃ to avoid repeated freeze/ thaw cycles.

产品性质

形式lyophilized powder
质量水平200
specific activity≥12 units/mg protein
运输dry ice
储存温度−20℃

安全信息

象形图GHS08
警示用语:Danger
危险声明H334
预防措施声明P261 - P284 - P304 + P340 + P312 - P501
危险分类Resp. Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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