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MBX-102

品牌
Sigma-Aldrich
CAS
24136-23-0
货号
SML0064
包装型号
规格纯度
≥98% (HPLC)
参考价格
1956.53 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

MBX-102 may be used in PPAR-mediated cell signaling studies.

包装

5, 25 mg in glass bottle

生化/生理作用

MBX-102 has a potent transrepression effect on PPARγ. It is an oral glucose-reducing agent and also has insulin-sensitizing properties. It is useful as treatment for type 2 diabetes. MBX-102 also lowers triglycerides in a PPARα-independent manner.
MBX-102 is a selective PPAR modulator (SPPARM) and has been shown to inhibit phosphorylation of PPARγ. MBX-102 is converted to the active form, MBX-102 acid, in vivo.

特点和优势

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the Nuclear Receptors (Non-Steroids) and Nuclear Receptors (PPARs) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

基本信息

经验(实验)分子式C19H17ClF3NO4
分子量415.79
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to tan
溶解性DMSO: ≥35 mg/mL
创始人Johnson & Johnson
储存温度2-8℃

安全信息

象形图GHS06GHS09
警示用语:Danger
危险声明H301 - H319 - H400
预防措施声明P273 - P301 + P310 + P330 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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