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Lipopolysaccharides from Proteus vulgaris

品牌
Sigma-Aldrich
货号
SMB00801
规格纯度
purified by phenol extraction
参考价格
2145.31 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Proteus vulgaris is a rod-shaped Gram-negative, facultative anaerobe bacterium. It inhabits the intestinal tract of humans and animals and can be found in soil, water and feces. P. vulgaris is a member of the Enterobacteriaceae family which are opportunistic pathogens in humans, responsible for urinary tract and burn infections.

Chemical structures of LPS from Proteus sp. are different from each other. These differences can be associated with the virulence and pathogenesis of the bacteria. It has been reported that the LPS chemical structure from P. vulgaris can influence the crystallization of mineral urine components (such as calcium and magnesium), resulting in stone formation in the kidney.

应用

Antibodies produced in rickettsial infections were found to react with LPS from Proteus vulgaris and Proteus mirabilis. This phenomenon allows the purified LPS from these two species to serve as a tool for diagnosis of rickettsiosis (scrub typhus, caused by the bacterium Orientia sp.) in the Weil-Felix test.

产品性质

生物来源bacterial (Proteus vulgaris)
质量水平200
形式lyophilized powder
纯化方式phenol extraction
杂质≤3% Protein (Lowry)
运输ambient
储存温度2-8℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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