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Human MMP-1 ELISA Kit

品牌
Sigma-Aldrich
货号
RAB0362
规格纯度
for cell and tissue lysates
参考价格
7209.4 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The Human MMP-1 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-1 cell lysate and tissue lysate.

免疫原

Recombinant Human MMP1

应用

请参考Protocol了解详情。

生化/生理作用

Matrix metalloproteinases (MMPs) enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular diseases, skeletal growth-plate disorders, and cancer metastasis. MMP-1 is a secreted collagenase with specificity toward Type I, II, III, VII, and X collagens, aggrecan, serpins, and α2-macroglobulin. It is overexpressed in lumbar intervertebral disc degeneration (IDD). It might also be associated with rheumatoid arthritis and osteoarthritis. MMP-1 is linked with juvenile idiopathic arthritis. Genetic variations in MMP-1 can affect the susceptibility and severity of this disease. MMP-1 might facilitate fibrous plaque disruption via degradation of interstitial collagens and thinning of the fibrous cap.

其他说明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

基本信息

NACRESNA.32

产品性质

species reactivityhuman
包装kit of 96 wells (12 strips x 8 wells)
technique(s)ELISA: suitable
capture ELISA: suitable
inputsample type cell lysate
sample type tissue lysate
assay rangeinter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/mL
standard curve range: 24.69-18000 pg/mL
detection methodcolorimetric
运输wet ice
储存温度−20℃
Gene Informationhuman ... MMP1(4312)

组份列表

组份可单独销售

货号组份
RABDIL6ELISA 5X Sample Diluent Buffer (Item D2)
RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)
RABLYSIS12X Cell Lysis Buffer (Item J)
RABSTOP3ELISA Stop Solution (Item I)
RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
RABWASH420X Wash Buffer (Item B)

安全信息

象形图GHS05
警示用语:Warning
危险声明H290
预防措施声明P234 - P390
危险分类Met. Corr. 1
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 3

Sigma-Aldrich

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