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GSTA1 human

品牌
Sigma-Aldrich
CAS
106804-04-0
货号
SRP6097
规格纯度
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
参考价格
6036.84 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Glutathione S-transferase A1 in humans is encoded by the GSTA1 gene. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. GSTA1 protects the cells from reactive oxygen species and is highly expressed in liver.
The gene encoding GSTA1 is localized on human chromosome 6p12.2.

生化/生理作用

GSTA1 (Glutathione S-transferase α1) is associated with the biosynthesis of steroids such as testosterone and progesterone. It plays a vital role in double bond isomerase activity. GSTA1 converts δ(5)-androstene-3,17-dione to δ(4)-androstene-3,17-dione. It has a role in the metabolism of several xenobiotics.

外形

1 mg/mL solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT and 10% glycerol.

制备说明

Centrifuge the vial prior to opening.

其他说明

MAEKPKLHYF NARGRMESTR WLLAAAGVEF EEKFIKSAED LDKLRNDGYL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKERA LIDMYIEGIA DLGEMILLLP VCPPEEKDAK LALIKEKIKN RYFPAFEKVL KSHGQDYLVG NKLSRADIHL VELLYYVEEL DSSLISSFPL LKALKTRISN LPTVKKFLQP GSPRKPPMDE KSLEEARKIF RF

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
测定≥90% (SDS-PAGE)
形式liquid
分子量 25.6 kDa
包装pkg of 100 μg
NCBI登记号P08263 
UniProt登记号P08263
运输dry ice
储存温度−70℃
Gene Informationhuman ... GSTA1(2938)

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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