产品说明
一般描述
GRB7 or growth factor receptor-bound protein 7 belongs to a small family of adapter proteins which interact with a number of receptor tyrosine kinases and signaling molecules. GRB7 encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. GRB7 is highly expressed in liver and kidney. GRB7 isoforms are involved in cell invasion and metastatic progression of human esophageal carcinomas. GRB7 plays an important role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK).
外形
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
制备说明
after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles
基本信息
| NACRES | NA.32 |
产品性质
| 重组 | expressed in E. coli |
| 测定 | ≥70% (SDS-PAGE) |
| 形式 | buffered aqueous glycerol solution |
| 分子量 | ~91 kDa |
| NCBI登记号 | NM_001030002 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... GRB7(2886) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
