产品说明
免疫原
The epitope recognized by PLA0045 maps to a region between residues 2550 and 2600 of human Ataxia Telangiectasia Mutated using the numbering given in entry NP_000042.2 (GeneID 472).
外形
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide
其他说明
Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA double-strand breaks (DSBs), ATM initiates a signaling cascade that involves the phosphorylation of a multitude of substrates which include p53, BRCA1, p53 binding protein, CHK2, RAD9, RAD17, and MDM4.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | goat |
| 抗体形式 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| 等级 | Powered by Bethyl Laboratories, Inc. |
| species reactivity | human |
| technique(s) | immunoprecipitation (IP): 2-5 μg/mg western blot: 1:2,000-1:10,000 |
| 登记号 | NP_000042.2 |
| UniProt登记号 | Q13315 |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| Gene Information | goat ... ATM(472) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
