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Fmoc-N-amido-dPEG®8-acid

品牌
Sigma-Aldrich
货号
QBD10273
包装型号
规格纯度
>95% (HPLC)
参考价格
1999.75 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

特点和优势

Fmoc-N-amido-dPEG8-acid is a monodisperse PEG product that is useful for peptide synthesis. The 28-atom dPEG spacer allows the introduction of a medium-length, hydrophilic spacer onto either end of a peptide chain or between two peptide chains. The flexible dPEG spacer conjugates to peptides using conventional peptide synthesis chemistry. Peptide PEGylation imparts water solubility to hydrophobic peptide chains. Also, PEGylated peptides have expanded hydrodynamic volumes, which can reduce or eliminate renal clearance, and are protected from proteolysis. The combination of decreased renal clearance and protection from proteolysis contributes to longer in vivo circulation times for PEGylated (as compared to non-PEGylated) peptides. Additionally, PEGylation diminishes a peptide′s antigenicity. This product is part of the Fmoc-N-amido-dPEGn-acid (n=2, 3, 4, 5, 6, 8, 12, 24, 36) product series.

法律信息

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

基本信息

经验(实验)分子式C34H49NO12
分子量663.75
MDL编号MFCD11041143

产品性质

测定>95% (HPLC)
形式solid or viscous liquid
reaction suitabilityreaction type: Pegylations
聚合物结构设计shape: linear
functionality: heterobifunctional
运输ambient
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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