产品说明
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
生化/生理作用
Fluibiprofen is a cyclooxygenase (COX) inhibitor, which is an enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This decreases the prostaglandins which cause inflammation, pain, swelling and fever. Flurbiprofen inhibits the activity of both COX-1 and -2. The S enantiomer inhibits prostaglandin synthesis and has both anti-inflammatory and analgesic activity, while the R enantiomer does not inhibit prostaglandin synthesis and displays only analgesic activity.
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
Sales restrictions may apply.
基本信息
| 线性分子式 | C6H5C6H3(F)CH(CH3)CO2H |
| 分子量 | 244.26 |
| MDL编号 | MFCD00079303 |
| PubChem化学物质编号 | 329749901 |
| NACRES | NA.24 |
产品性质
| 等级 | pharmaceutical primary standard |
| manufacturer/tradename | USP |
| mp | 110-112 ℃ (lit.) |
| application(s) | pharmaceutical (small molecule) |
| 格式 | neat |
| SMILES string | CC(C(O)=O)c1ccc(c(F)c1)-c2ccccc2 |
| InChI | 1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18) |
| InChI key | SYTBZMRGLBWNTM-UHFFFAOYSA-N |
| Gene Information | human ... PTGS1(5742), PTGS2(5743) |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H301 |
| 预防措施声明 | P301 + P330 + P331 + P310 |
| 危险分类 | Acute Tox. 3 Oral |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
