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Fingolimod Hydrochloride

2-氨基-2- [2-(4-辛基-苯基)-乙基]-丙烷-1,3-二醇 盐酸盐

品牌
USP
CAS
162359-56-0
货号
1270480
规格纯度
United States Pharmacopeia (USP) Reference Standard
参考价格
29022.3 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Fingolimod Hydrochloride (fingolimod HCl), an S1P-receptor modulator, belongs to the class of synthetic glucocorticoid steroid drugs.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Fingolimod Hydrochloride USP reference standard may be used to quantify the analyte in gel, capsule and other pharmaceutical formulations, active pharmaceutical ingredient (API) and pharmaceutical dosage forms by liquid chromatography (LC) based techniques.

生化/生理作用

FTY720是一种免疫调节药物以及1-磷酸鞘氨醇(S1P)受体的调节剂。 鞘氨醇激酶对FTY270的磷酸化可导致S1P1R的内化,从而螯合淋巴结中的淋巴细胞,阻止它们参与自身免疫反应。 临床上,它已被批准用于治疗多发性硬化症(MS)。研究显示其可通过抑制S1PR阻断和逆转紫杉醇诱导的化疗诱导的周围神经病变(CIPN),并可抑制小鼠脑海马中组蛋白脱乙酰酶的活性,从而调节记忆。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C19H33NO2 · HCl
分子量343.93

产品性质

生物来源synthetic
agencyUSP
形式powder
manufacturer/tradenameUSP
储存条件protect from light
颜色 white
溶解性DMSO: soluble
ethyl acetate: soluble
water: soluble
application(s)pharmaceutical
储存温度2-8℃
InChI1S/C19H33NO2.ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22;/h9-12,21-22H,2-8,13-16,20H2,1H3;1H
InChI keySWZTYAVBMYWFGS-UHFFFAOYSA-N

安全信息

象形图GHS08
警示用语:Warning
危险声明H373
预防措施声明P260 - P314 - P501
危险分类STOT RE 2
靶器官Immune system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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