产品说明
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
生化/生理作用
泛昔洛韦是一种抗逆转录病毒鸟苷类似物，用于治疗疱疹病毒感染和乙肝。泛昔洛韦可迅速转化为喷昔洛韦。病毒胸苷激酶将喷昔洛韦磷酸化为单磷酸形式，然后细胞激酶又将其转换为三磷酸喷昔洛韦。喷昔洛韦三磷酸可竞争性抑制病毒 DNA 聚合酶，从而抑制病毒复制。长时间服用会形成耐药性；这通常表现为筛选出了一批 DNA 聚合酶基因逆转录酶结构域突变的预先存在的耐药性菌株。
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
USP issued SDS can be found here.
Sales restrictions may apply.
基本信息
| 经验(实验)分子式 | C14H19N5O4 |
| 分子量 | 321.33 |
| MDL编号 | MFCD00866964 |
| PubChem化学物质编号 | 329749829 |
| NACRES | NA.24 |
产品性质
| 等级 | pharmaceutical primary standard |
| manufacturer/tradename | USP |
| application(s) | pharmaceutical (small molecule) |
| 格式 | neat |
| 储存温度 | 2-8℃ |
| SMILES string | CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O |
| InChI | 1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18) |
| InChI key | GGXKWVWZWMLJEH-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
