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COX-2 Inhibitor screening kit

品牌
Sigma-Aldrich
货号
MAK399
规格纯度
sufficient for 100 fluorometric tests
参考价格
5798.98 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Cyclooxygenase (COX), also known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme that is responsible for the formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane. COX is the central enzyme in the biosynthetic pathway to prostanoids from arachidonic acid. There are two known isoenzymes: COX-1 and COX-2. COX-1 is constitutively expressed in many tissues and is the predominant form in gastric mucosa and in kidney. COX-2 is not expressed under normal conditions in most cells, but elevated levels are found during inflammation. Pharmacological inhibition of COX by non-steroidal anti-inflammatory drugs (NSAID) can provide relief from the symptoms of inflammation and pain.

特点和优势

COX-2 Inhibitor Screening Kit:

  • Compatible with high-throughput handling systems.

适用性

The kit is suitable for screening, studying and characterizing COX-2 inhibitors.

原理

The assay is based on the fluorometric detection of Prostaglandin G2, the intermediate product generated by the COX enzyme.

产品性质

质量水平100
web metadata keyword.defaultCOX-2 Inhibitor Screening Kit|sigma-aldrich
detection methodfluorometric
储存温度−20℃

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 3

Sigma-Aldrich

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