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CNTN2/Contactin-2 human

品牌
Sigma-Aldrich
货号
SRP6447
规格纯度
recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
参考价格
3563.77 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Contactin-2 also known as CNTN2, TAX1 (transiently-expressed axonal glycoprotein), TAG1 (transient axonal glycoprotein), and axonin-1, and is a member of the immunoglobulin superfamily. CNTN2 consists of six Ig-like domains and four fibronectin type III domains, and is anchored to the membrane by glycosylphosphatidylinositol (GPI), whereas the soluble form can be released by a GPI-specific phospholipase. As a neural cell adhesion molecule expressed by a subset of neuronal populations in the developing CNS and PNS, CNTN2 mediates cell-cell interactions either via homophilic, or heterophilic contacts with various adhesion molecules including NgCAM, NrCAM, NCAM and neurocan. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.

外形

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.

重悬

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in HEK 293 cells
测定≥95% (SDS-PAGE)
形式lyophilized
分子量calculated mol wt 109 kDa
observed mol wt 140 kDa by SDS-PAGE (reducing) (Ser 31 is the predicted N-terminal .)
包装pkg of 10 and 50 μg
杂质<1 EU/μg endotoxin (LAL test)
UniProt登记号Q02246
运输wet ice
储存温度−20℃
Gene Informationhuman ... CNTN2(6900)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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