产品说明
一般描述
Cefiderocol is a novel injectable siderophore cephalosporin, which was formerly known as S-649266.(1)(3) It has a catechol-type siderophore and cephalosporin core and side chains.(1) Cefiderocol has structural similarity with both ceftazidime and cefepime, besides the chlorocatechol group on the end of the C-3 chain.(2)
生化/生理作用
Cefiderocol has strong antimicrobial properties especially against a wide spectrum of Gram-negative pathogens.(1)(3) Due to its siderophore core, it is also a natural iron-chelator, which adds to its antibacterial activities.(1)
基本信息
经验(实验)分子式 | C30H34ClN7O10S2 |
分子量 | 752.21 |
MDL编号 | MFCD30533432 |
产品性质
质量水平 | 100 |
测定 | ≥95% (HPLC) |
抗生素抗菌谱 | Gram-negative bacteria |
作用机制 | protein synthesis | inhibits |
储存温度 | −20℃ |
SMILES string | NC1=NC(/C(C(N[C@@H]2C(N3[C@@H]2SCC(C[N+]4(CCCC4)CCNC(C5=CC=C(O)C(O)=C5Cl)=O)=C3C([O-])=O)=O)=O)=N/OC(C(O)=O)(C)C)=CS1 |