位置:首页 > 品牌 > Sigma-Aldrich >

CD48/BCM1/SLAMF2 human

品牌
Sigma-Aldrich
货号
SRP6387
规格纯度
recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
参考价格
3487.6 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.
CD48 (cluster of differentiation 48) is soluble receptor, expressed on haematopoietic cell surface. It is a glycosylphosphatidylinositol anchored protein and belongs to the CD2 family. The CD48 gene is mapped to human chromosome 1q23.3.

生化/生理作用

Eosinophil cells expressing CD48 (cluster of differentiation 48) receptors play an important role in allergic reactions induced by toxins such as those produced by Staphylococcus aureus. CD48 acts as a costimulator to activate T-lymphocytes as part of immune response. It also serves as an adhesion molecule.

外形

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

重悬

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in HEK 293 cells
标签6-His tagged (C-terminus)
测定≥95% (SDS-PAGE)
形式lyophilized
分子量calculated mol wt 23.2 kDa
observed mol wt 38-45 kDa (DTT-reduced. Protein migrates due to glycosylation. Gln 27 is the predicted N-terminus.)
包装pkg of 10 μg
pkg of 50 μg
杂质<1 EU/μg endotoxin (LAL test)
UniProt登记号P09326
运输wet ice
储存温度−20℃
Gene Informationhuman ... CD48(962)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号