产品说明
包装
10, 50 mg in glass bottle
生化/生理作用
Caged MK801 is an inactive caged form of the potent selective non-competitive irreversible NMDA glutamate receptor open-channel blocker MK801. Caged MK801 is cleaved by exposure to UV light, liberating the active MK801. The caged compound is stable within cells. Intracellular compartment-specific photorelease allowed study the locus of induction and expression of timing-dependent long-term depression (t-LTD). Caged MK801 is thus a useful tool to uncover compartment-specific biological functions.
特点和优势
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
经验(实验)分子式 | C26H24N2O6 |
分子量 | 460.48 |
PubChem化学物质编号 | 329825309 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
储存条件 | protect from light |
颜色 | white to light yellow |
溶解性 | DMSO: ≥10 mg/mL |
储存温度 | 2-8℃ |
SMILES string | COc1cc(COC(=O)N2[C@@H]3Cc4ccccc4[C@@]2(C)c5ccccc35)c(cc1OC)[N+]([O-])=O |
InChI | 1S/C26H24N2O6/c1-26-19-10-6-4-8-16(19)12-22(18-9-5-7-11-20(18)26)27(26)25(29)34-15-17-13-23(32-2)24(33-3)14-21(17)28(30)31/h4-11,13-14,22H,12,15H2,1-3H3/t22-,26+/m1/s1 |
InChI key | WZDXUEMCALAOAY-GJZUVCINSA-N |