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BRD1 (556-688) his tag human

品牌
Sigma-Aldrich
货号
SRP6411
规格纯度
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
参考价格
5893.01 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. BRD1 is a bromodomain containing protein that has been identified as a susceptibility gene in neurological disorders, such as schizophrenia and bipolar affective disorder. This protein can be used for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling. Recombinant human BRD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

外形

0.5 mg/mL in Phosphate buffer saline (pH 7.4) containing 10% glycerol and 1mM DTT.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
测定≥95% (SDS-PAGE)
形式liquid
分子量 17.8 kDa (156 aa, 556-688 aa + His Tag)
包装pkg of 100 μg
浓度0.5 mg/mL
UniProt登记号O95696
运输dry ice
储存温度−70℃
Gene Informationhuman ... BRD1(23774)

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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