产品说明
特点和优势
Biotin-dPEG®4-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety which hydrolyzes more slowly than NHS ester in aqueous media and are more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG®4-TFP ester has a long spacer of precise length (19.2 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. The PEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
基本信息
经验(实验)分子式 | C27H37F4N3O8S |
分子量 | 639.66 |
PubChem化学物质编号 | 329823873 |
NACRES | NA.22 |
产品性质
测定 | >90% |
形式 | solid or viscous liquid |
reaction suitability | reaction type: Biotinylations reaction type: Biotinylations reactivity: amine reactive reagent type: cross-linking reagent |
聚合物结构设计 | shape: linear functionality: monofunctional |
运输 | ambient |
储存温度 | −20℃ |
SMILES string | O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |