产品说明
特点和优势
Biotin-dPEG®12-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety whcih hydrolyze more slowly than NHS esters in aqueous media and is more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG®12-TFP ester has a long spacer of precise length (47.6 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the PEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
基本信息
| 经验(实验)分子式 | C43H69F4N3O16S |
| 分子量 | 992.08 |
| PubChem化学物质编号 | 329823872 |
| NACRES | NA.22 |
产品性质
| 测定 | >90% |
| 形式 | solid or viscous liquid |
| reaction suitability | reaction type: Biotinylations reaction type: Biotinylations reactivity: amine reactive reagent type: cross-linking reagent |
| 聚合物结构设计 | shape: linear functionality: monofunctional |
| 运输 | ambient |
| 储存温度 | −20℃ |
| SMILES string | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O)OC3=C(C(F)=CC(F)=C3F)F |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
